Forging Links between Human Mental Retardation–Associated CNVs and Mouse Gene Knockout Models
نویسندگان
چکیده
منابع مشابه
Forging Links between Human Mental Retardation–Associated CNVs and Mouse Gene Knockout Models
Rare copy number variants (CNVs) are frequently associated with common neurological disorders such as mental retardation (MR; learning disability), autism, and schizophrenia. CNV screening in clinical practice is limited because pathological CNVs cannot be distinguished routinely from benign CNVs, and because genes underlying patients' phenotypes remain largely unknown. Here, we present a novel...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2009
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1000531